Dr Dear began his medical training at University College London and completed a PhD in Pharmacology before finishing his clinical training at Brasenose College, Oxford University. After junior medical jobs at the John Radcliffe Hospital in Oxford and a variety of London teaching hospitals, Dr Dear spent 2 years at a research fellow at the National Institutes of Health, Bethesda, USA. This time was spent learning proteomic and imaging techniques as applied to acute kidney injury. Since 2005, Dr Dear has been a Clinical Lecturer then Consultant/ Honorary Senior Clinical Lecturer in Clinical Pharmacology at the Royal Infirmary of Edinburgh/Edinburgh University. In 2012, Dr Dear was awarded an NHS Research Scotland (NRS) Career Research Fellowship. Current research interests are markers and mediators of paracetamol toxicity and kidney cell-derived exosomes: key inter-cellular messengers and vehicles for cell-specific drug delivery.