Toxicological analysis in Alternative Samples
Based upon examples from own work and recent literature, this lecture will provide a condensed overview of alternative sampling strategies that are being applied in toxicology. In alternative sampling strategies, a ‘classical’ sample can be obtained in an alternative way (dried blood spots are a typical example) or ‘non-classical’ samples (different from urine or blood, plasma or serum) can be collected. Typical examples of the latter are hair, nails, oral fluid, breath and meconium. The possibilities and advantages of the different approaches will be discussed, along with their limitations.
- Being able to situate the position of alternative sampling strategies in toxicology
- Being aware of the pros and cons of the different strategies
- Being able to say in why in a given situation a particular alternative sampling strategy may (or may not) be an option